{"id":14,"date":"2026-10-12T06:37:34","date_gmt":"2026-10-12T06:37:34","guid":{"rendered":"https:\/\/fgvhp.com\/applications\/biosafety-lab-decontamination\/"},"modified":"2026-10-12T06:37:34","modified_gmt":"2026-10-12T06:37:34","slug":"biosafety-lab-decontamination","status":"publish","type":"page","link":"https:\/\/fgvhp.com\/ru\/applications\/biosafety-lab-decontamination\/","title":{"rendered":"VHP \u0434\u043b\u044f \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u0439 \u0431\u0438\u043e\u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0438, \u0431\u043e\u043a\u0441\u043e\u0432 \u0431\u0438\u043e\u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0438 \u0438 \u043a\u043e\u0440\u043f\u0443\u0441\u043e\u0432 \u0444\u0438\u043b\u044c\u0442\u0440\u043e\u0432 BIBO"},"content":{"rendered":"\n\n
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Home<\/a> \/ Applications<\/a> \/ Biosafety labs & filter housings<\/span><\/div>\n Application \u00b7 Biosafety & containment<\/span>\n

VHP for Biosafety Labs, BSCs and BIBO Filter Housings<\/h1>\n

Before a contaminated HEPA filter is changed, a biosafety cabinet is serviced or a containment lab is handed over for maintenance, the air path and surfaces must be decontaminated \u2014 with the containment boundary still intact.<\/p>\n

Request a Free Application Review<\/a><\/div>\n <\/div>\n
\"Fenggu<\/div>\n<\/div><\/section>\n\n
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The challenge<\/span>

Why this needs a VHP step<\/h2><\/div>\n

In containment work the risk is the reverse of aseptic processing: the hazard is inside, and it must not reach the maintenance technician or the environment. Filters, ductwork and cabinet plenums collect the material that is hardest to clean by hand.<\/p>

Connecting a VHP generator to the housing or cabinet treats the enclosed air path in place, so the filter can then be changed using the bag-in\/bag-out procedure with a validated decontamination behind it.<\/p><\/div>\n<\/div><\/section>\n\n

\n Typical configuration<\/span>

Equipment options<\/h2>\n
FG-VHP-BIBO<\/span>

VHP BIBO sterilizer<\/h3>

Connects to the BIBO housing valve. Molecular-sieve dehumidification to < 30% RH, approx. 30 ppm for ~40 min, residual removed by palladium catalyst or the BIBO supply\/exhaust system.<\/p>View specifications \u2192<\/span><\/a>FG-VHP-GL<\/span>

Recirculating VHP generator<\/h3>

Forms a closed loop with biosafety cabinets, centrifuges and other enclosed equipment through supply and return tubing.<\/p>View specifications \u2192<\/span><\/a><\/div>\n \n

Key specifications<\/h3>\n
<\/th>BIBO sterilizer (FG-VHP-BIBO)<\/th>Recirculating generator (FG-VHP-GL)<\/th><\/tr><\/thead>
Treatment volume<\/th>\u2264 30 m\u00b3<\/td>Enclosed equipment<\/td><\/tr>
Dehumidification<\/th>< 30% RH<\/td>< 50% RH space humidity<\/td><\/tr>
VHP concentration<\/th>approx. 30 ppm, ~40 min<\/td>300\u2013700 ppm<\/td><\/tr>
Residual<\/th>\u2264 1 ppm (catalytic)<\/td>\u2264 1 ppm<\/td><\/tr>
Dimensions<\/th>640 \u00d7 836 \u00d7 1,036 mm<\/td>600 \u00d7 600 \u00d7 1,100 mm<\/td><\/tr>
Sporicidal efficacy<\/th>\u2265 6-log (subject to validation)<\/td>\u2265 6-log (subject to validation)<\/td><\/tr><\/tbody><\/table><\/div>\n

Figures from Fenggu product specifications. Cycle times and efficacy are confirmed by validation for your space and load.<\/p>\n<\/div><\/section>\n\n

\n Engineering & validation<\/span>

What to plan for<\/h2>\n
01<\/span>

Keep containment during the cycle<\/h3>

Plan how the housing or cabinet stays negative or sealed while vapour is injected and recirculated, and where any exhaust goes.<\/p><\/div>

02<\/span>

Gas-tight isolation<\/h3>

Bubble-tight dampers or valves upstream and downstream of the filter define the treated volume. Without them, vapour escapes into the duct system and concentration is lost.<\/p><\/div>

03<\/span>

Indicators on both filter faces<\/h3>

Place biological indicators on the upstream (dirty) face and downstream side of the filter, and in the housing corners, to prove the air path \u2014 not just the open volume.<\/p><\/div>

04<\/span>

Filter media takes up peroxide<\/h3>

HEPA media and gaskets absorb vapour, which slows the rise to target concentration and extends aeration. Allow for it in cycle development.<\/p><\/div>

05<\/span>

Document the hand-over<\/h3>

Record the cycle, BI results and residual reading as part of the maintenance permit, so the technician starts work with evidence the system is safe.<\/p><\/div><\/div>\n<\/div><\/section>\n\n

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Before you ask for a quote<\/span>

Information an engineer will need<\/h2>

Having these ready makes the first recommendation specific instead of generic.<\/p><\/div>\n

  • Housing or cabinet type and volume<\/li>
  • Connection points (valves, test ports)<\/li>
  • Isolation damper arrangement<\/li>
  • Biological agents handled (risk group)<\/li>
  • How exhaust is managed during the cycle<\/li>
  • Maintenance and filter-change frequency<\/li><\/ul>\n<\/div><\/section>\n\n\n
    \n FAQ<\/span>

    Common questions<\/h2>\n
    Does the filter have to be removed before decontamination?<\/summary>

    No. The point of in-situ decontamination is to treat the filter while it is still sealed in the housing, then change it.<\/p><\/details>

    Can the same generator treat a whole BSL-3 lab?<\/summary>

    A BIBO sterilizer is sized for housings and enclosed volumes up to 30 m\u00b3. Whole rooms are usually treated with a mobile room unit or an HVAC-integrated system.<\/p><\/details>

    How is the cycle proven?<\/summary>

    With biological indicators, typically Geobacillus stearothermophilus spore carriers, placed at worst-case locations, and a residual measurement before the housing is opened.<\/p><\/details><\/div>\n<\/div><\/section>\n